×
Entrez Id: 729
Gene Symbol: C6
C6
Chronic kidney disease stage 5
0.200
ModifyingMutation
RGD
C6 mediates chronic progression of tubulointerstitial damage in rats with remnant kidneys.
11912252 2002
×
Entrez Id: 1636
Gene Symbol: ACE
ACE
Chronic kidney disease stage 5
0.300
Therapeutic
RGD
Carbonic adsorbent AST-120 retards progression of renal failure by additive effect with ACEI and protein restriction diet.
14586729 2003
×
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
Chronic kidney disease stage 5
0.290
Therapeutic
RGD
Effect of exercise on cardiac tissue oxidative and inflammatory mediators in chronic kidney disease.
18797164 2009
×
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
Chronic kidney disease stage 5
0.230
Therapeutic
RGD
[Effects of shenshuai II recipe on the protein expressions of Ang II and nNOS in chronic renal failure rats' nephridial tissue].
23185775 2012
×
Entrez Id: 596
Gene Symbol: BCL2
BCL2
Chronic kidney disease stage 5
0.210
Therapeutic
RGD
Epoetin delta as an antifibrotic agent in the remnant kidney rat: a possible role for transforming growth factor beta and hepatocyte growth factor.
20424483 2010
SERPINE1
Chronic kidney disease stage 5
0.210
Therapeutic
RGD
An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure.
26903149 2016
×
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
Chronic kidney disease stage 5
0.200
Therapeutic
RGD
Delivery of recombinant adeno-associated virus-mediated human tissue kallikrein for therapy of chronic renal failure in rats.
18402547 2008
×
Entrez Id: 2147
Gene Symbol: F2
F2
Chronic kidney disease stage 5
0.200
Therapeutic
RGD
5/6 nephrectomy as a validated rat model mimicking human warfarin-related nephropathy.
22473220 2012
×
Entrez Id: 5734
Gene Symbol: PTGER4
PTGER4
Chronic kidney disease stage 5
0.200
Therapeutic
RGD
Role of EP2 and EP4 receptor-selective agonists of prostaglandin E(2) in acute and chronic kidney failure.
16871242 2006
×
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
Chronic kidney disease stage 5
0.200
Therapeutic
RGD
Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model.
22427849 2012
×
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Chronic kidney disease stage 5
0.300
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144 2014
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
Chronic kidney disease stage 5
0.300
Biomarker
RGD
Oral sorbent AST-120 increases renal NO synthesis in uremic rats.
18089446 2008
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Chronic kidney disease stage 5
0.300
Biomarker
RGD
Only animals from the 1WIK group developed severe chronic renal failure , glomerulosclerosis, interstitial fibrosis, and upregulation of transforming growth factor-beta(1 ) (TGF-beta(1 )) gene, which was associated with increased TGF-beta(1 ) protein expression in tubular epithelial cells, arterioles, and in areas of mononuclear interstitial cell infiltrate.
10919844 2000
×
Entrez Id: 5741
Gene Symbol: PTH
PTH
Chronic kidney disease stage 5
0.300
Biomarker
RGD
Two novel vitamin D receptor modulators with similar structures exhibit different hypercalcemic effects in 5/6 nephrectomized uremic rats.
23548814 2013
×
Entrez Id: 9365
Gene Symbol: KL
KL
Chronic kidney disease stage 5
0.300
Biomarker
RGD
This is the first report showing the expression of the klotho gene in the kidney is regulated under sustained circulatory stress such as long-term hypertension, diabetes mellitus, and chronic renal failure .
9731228 1998
×
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
Chronic kidney disease stage 5
0.290
Biomarker
RGD
Expression of monocyte chemoattractant protein-1 in proximal tubular epithelial cells in a rat model of progressive kidney failure.
12080327 2002
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Chronic kidney disease stage 5
0.280
Biomarker
RGD
Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.
22031851 2012
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Chronic kidney disease stage 5
0.280
Biomarker
RGD
Multiple antioxidants and L-arginine modulate inflammation and dyslipidemia in chronic renal failure rats.
20199183 2010
×
Entrez Id: 1234
Gene Symbol: CCR5
CCR5
Chronic kidney disease stage 5
0.260
Biomarker
RGD
Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats.
19535570 2009
×
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
Chronic kidney disease stage 5
0.260
Biomarker
RGD
Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure.
20631677 2010
×
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
Chronic kidney disease stage 5
0.250
Biomarker
RGD
Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure.
19420110 2009
×
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
Chronic kidney disease stage 5
0.240
Biomarker
RGD
Renal endothelin gene expression is increased in remnant kidney and correlates with disease progression.
8441230 1993
×
Entrez Id: 51094
Gene Symbol: ADIPOR1
ADIPOR1
Chronic kidney disease stage 5
0.230
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144 2014
×
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
Chronic kidney disease stage 5
0.230
Biomarker
RGD
Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat.
17200156 2007
×
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
Chronic kidney disease stage 5
0.220
Biomarker
RGD
Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats.
19535570 2009